NFL Fantasy 2025 Start 'Em, Sit 'Em: Defenses for Week 16

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You have lineup questions, we have lineup answers — at least we hope so. Start ‘Em, Sit ‘Em is here to help fantasy managers make difficult roster decisions. And you know what is a good move? Starting Jahmyr Gibbs. But that’s too obvious, so you won’t see such simple analysis here. Instead, we’re exploring more debatable situations. And if you can’t find a player you are looking for, please check out the latest NFL Fantasy lineup rankings.

NOTE: Unless otherwise indicated, all stats come from NFL Pro, Next Gen Stats or NFL Research.

Start ‘Em

VS.

Big defensive fantasy performances against the Raiders are becoming more and more common. With     Kenny Pickett     starting for Las Vegas last week, the Eagles picked up four sacks, one takeaway and shut out the Raiders. That offense is in shambles. It is top two in fantasy PPG allowed to defenses this season. It has taken sacks at the highest rate in the NFL and has struggled to protect the ball. Houston brings week-winning upside in this one, no matter who’s playing quarterback for Vegas.

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