NFL Fantasy 2025 Start 'Em, Sit 'Em: Defenses for Week 5

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You have lineup questions, we have lineup answers — at least we hope so. Start ‘Em, Sit ‘Em is here to help fantasy managers make difficult roster decisions. And you know what is a good move? Starting Puka Nacua. But that’s too obvious, so you won’t see such simple analysis here. Instead, we’re exploring more debatable situations. And if you can’t find a player you are looking for, please check out the latest NFL Fantasy lineup rankings.

NOTE: Unless otherwise indicated, all stats come from NFL Pro, Next Gen Stats or NFL Research.

Start ‘Em

VS.

The Titans have allowed sacks and pressure at the second-highest rate in the NFL. Drops have also been an issue, as the receivers continue to make life as tough as possible on their rookie QB. And they’ve unsurprisingly struggled to put points on the board. It’s why three of the four defenses they faced this season have scored at least 13 fantasy points against them … and the other one scored eight. The Titans are the top team to stream against.

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