NFL Fantasy 2025 Start 'Em, Sit 'Em: Quarterbacks for Week 16

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You have lineup questions, we have lineup answers — at least we hope so. Start ‘Em, Sit ‘Em is here to help fantasy managers make difficult roster decisions. And you know what is a good move? Starting Jahmyr Gibbs. But that’s too obvious, so you won’t see such simple analysis here. Instead, we’re exploring more debatable situations. And if you can’t find a player you are looking for, please check out the latest NFL Fantasy lineup rankings.

NOTE: Unless otherwise indicated, all stats come from NFL Pro, Next Gen Stats or NFL Research.

Start ‘Em

VS.

Last week, I went the cautious route with Brissett in the toughest possible matchup for quarterbacks: the Texans defense. He did what he has done all year, topping 18 fantasy points. Brissett became the top-scoring QB in a game against Houston (20.56). He also became the first to throw three TDs versus the Texans and the first to finish as a top-12 fantasy QB in his week against the vaunted D. Last week was the test week for Brissett. If he found success in that matchup, he is indeed matchup-proof. Now he gets the Falcons, who have allowed the fourth-most passing yards and sixth-most TDs to quarterbacks since Week 10. Brissett is a strong start this week, and then he gets the Bengals in championship week. As my colleague Marcas Grant says, Brissett it and forget it!

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