Safest players to pick in Round 4 or later in 2025 fantasy football drafts

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Finding safe players — those who have a high probability to be solid producers — in the middle rounds of your fantasy drafts can give you an edge over your league-mates. There are good players who fall in drafts every year, perhaps because they are older, seem like boring picks, dealt with injury last season or lack top-10 upside … but you can’t swing for the fences on every pick.

Below are seven players who will likely be available in Round 4 or later to provide your team with a reliably high floor and bankable production. Average draft position (ADP) is pulled from Fantasy Pros, based on 12-team PPR leagues.

Despite playing without Christian McCaffrey, Brandon Aiyuk, Ricky Pearsall and All-Pro LT Trent Williams for large chunks of last season, Purdy still finished as the QB12 in fantasy points per game. He got off to a slow start but averaged nearly 19 fantasy PPG in Weeks 6-17 (he did not play in Weeks 12 and 18), scoring at least 17 points in eight of his 10 games. His two bad games came in a blizzard at Buffalo in Week 13 and during a downpour at home in Week 15. Among QBs over the last two seasons, only Josh Allen, Lamar Jackson and Jalen Hurts have notched more 20-plus fantasy point games than Purdy; those three will likely be selected at the top of fantasy drafts, while Purdy can be had in the ninth round.

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