NFL Fantasy 2025 Start 'Em, Sit 'Em: Defenses for Week 8

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You have lineup questions, we have lineup answers — at least we hope so. Start ‘Em, Sit ‘Em is here to help fantasy managers make difficult roster decisions. And you know what is a good move? Starting Justin Jefferson. But that’s too obvious, so you won’t see such simple analysis here. Instead, we’re exploring more debatable situations. And if you can’t find a player you are looking for, please check out the latest NFL Fantasy lineup rankings.

NOTE: Unless otherwise indicated, all stats come from NFL Pro, Next Gen Stats or NFL Research.

Start ‘Em

VS.

The Titans may have fired Brian Callahan last week, but they very much remain a top offense to stream against in fantasy. Last week, the Patriots defense had five sacks, two takeaways, scored a touchdown and had 19 fantasy points. Tennessee has allowed 13+ fantasy points to the opposing defense in four of their last five, including 16-plus in two straight. The Colts are a must play defense this week.

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